6-OHDA Lesion

Definition: 6-OHDA Lesion (6-hydroxydopamine) is a lesion model of Parkinson’s Disease in which 6-OHDA is microinjected into different regi...

Alpha-synuclein

Definition Alpha-synuclein (α-synuclein) is encoded by the SCNA gene and is found to be mutated in 5-10% of Parkinson’s Disease (PD) ...

Definition: Animal models are non-human species used in biomedical research for the investigation of human development and disease. Outcome: Anim...

Definition Bone infections also known as osteomyelitis can occur post injury or surgery. Bone infections can impair vascularization of bone tissu...

Definition Cardiometabolic diseases are comorbid disorders of the cardiovascular system and endocrine system. Examples of cardiometabolic disease...

Definition Cell therapy is the transplantation of cells to replace lost or damaged cells. Current Cell Therapies Cell therapies are used to trea...

Definition Immunofluorescence (IF) is an immunoassay used to identify a protein of interest in tissues or cells by labeling the protein with fluo...

Definition Juvenile diabetes also known as type 1 diabetes mellitus (T1D) is an endocrine and autoimmune disorder in which pancreatic insulin-pro...

Definition Lewy bodies are neuronal inclusions or clumps of mutated proteins that form aggregates and buildup throughout the brain. In patients w...

Definition In humans, the microbiome includes all microorganisms (bacteria, virus, fungi) on and inside of the body. Microbiome therapeutics use ...