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Discover precision histology services at our AniLocus. We offer expert histopathology solutions for your research. We excel in tissue analysis, helping you unveil cellular secrets and disease insights. Our experienced team, cutting-edge equipment, and streamlined protocols ensure accurate, timely results. Whether you’re in preclinical studies, drug development, or basic research, our histology services elevate your work. Contact us to unravel the intricacies of tissue structure and pathology.

Service Description Estimated Cost Range Fixative Requirements Approximate Assay Time
Tissue Sectioning Thin tissue section preparation $150 per sample 10% Neutral Buffered Formalin 1-3 business days
Special Stains Stains for specific tissue components $200 per stain 10% Neutral Buffered Formalin 2-5 business days
Immunofluorescence Staining Fluorescent labeling of specific proteins $250 per slide Formaldehyde-based fixative 1-2 business days
Cryosectioning Frozen tissue section preparation $175 per block None (frozen samples) 1-3 business days
H&E Staining Hematoxylin and eosin staining $50 per slide 10% Neutral Buffered Formalin 1-2 business days
Immunohistochemistry (IHC) Detection of specific antigens $300 per slide Formaldehyde-based fixative 2-4 business days
Frozen Sectioning Cutting frozen tissue sections $175 per block None (frozen samples) 1-2 business days
Image Analysis Quantitative analysis of stained slides $200 per slide/image None Varies based on analysis
RNA Scope Visualization of RNA molecules Varies 10% Neutral Buffered Formalin 2-5 business days
Laser Microdissection Isolation of specific tissue regions $500 per sample 10% Neutral Buffered Formalin 2-4 business days
Brightfield Imaging Standard microscopy imaging $100 per slide/image None Varies based on analysis
Fluorescence Imaging Fluorescent microscopy imaging $150 per slide/image None Varies based on analysis
Serial Sectioning Multiple sections from a single block $300 per block 10% Neutral Buffered Formalin 1-3 business days
*The exact cost and timeframes can vary and are subject to change at anytime.

Contact us to learn more about our histology CRO services:

Special Stains

Service Description Histopathology Estimated Cost Range Approximate Results Turnaround Time
Oil Red O Stain Detection of lipids in tissues Lipid droplets in liver or adipose tissue $75 – $150 per slide 2-3 business days
Wright-Giemsa Stain Hematology staining for blood cell differentiation Blood cell morphology assessment $75 – $150 per slide 2-3 business days
Silver Staining Detection of reticulin fibers Nucleolar structures in various tissues $75 – $200 per slide 2-4 business days
Acid Fast Ziehl-Neelsen Detection of Mycobacteria Nucleolar structures in various tissues $20-$50 per slide 1-2 business days
Alcian Blue Stains acidic mucosubstances in histology Mucin detection in various tissues $15 to $40 per slide 1-2 business days
Congo Red Stains amyloid deposits in histology Amyloid deposits in multiple organs $20 to $60 per slide 1-2 business days
Giemsa Stain Stain highlights cell nuclei and blood smears Blood cell morphology assessment $10 to $30 per slide 1-2 business days
Gram-Brown Hopps Stains bacteria Bacterial presence in various tissues $15 to $40 per slide 1-2 business days
Periodic Acid-Schiff (PAS) Stain Detection of glycogen, mucin, and fungal organisms Mucin and glycogen detection $15 to $40 per slide 1-2 business days
Perls Prussian Blue Detects iron deposits Iron content assessment in various tissues $20 to $60 per slide 1-2 business days
Toluidine Blue Detects mast cells and acidic mucosubstances Mast cell detection in multiple tissues $15 to $40 per slide 1-2 business days
Trichrome Masson’s Collagen and muscle fiber staining Fibrous/fibrotic tissue $15 to $40 per slide 1-2 business days
Von-Kossa Detects calcium deposits Bone $20 to $60 per slide 1-2 business days
Halls Bilirubin Detects bilirubin Liver $15 to $40 per slide 1-2 business days
Rubeanic Acid Detects copper Liver tissue (Wilson’s disease) $20 to $60 per slide 1-2 business days
Feulgen reaction Stains DNA for cytogenetic analysis DNA content and integrity $15 to $40 per slide 1-2 business days
GMS Gomori Methenamine Silver Detects fungal organisms Validating fungal infections in tissue $20 to $60 per slide 1-2 business days
LFB/PAS Stain Detects myelin and mucosubstances validating demyelination in central nervous system tissue; Multiple Sclerosis $15 to $40 per slide 1-2 business days
Mucicarmine Detects mucin Mucin-producing tumor tissue; Gastrointestinal and pancreatic cancer $20 to $60 per slide 1-2 business days
PAS/Alcian Blue Detects mucosubstances and glycogen Cancer and glycogen storage disease studies $20 to $60 per slid 1-2 business days
Phosphotungstic acid haematoxylin (PTAH) Stains muscle and collagen Neuromuscular disorder and fibrosis studies $20 to $60 per slide 1-2 business days
Reticulin Stain Gomori Stain highlights reticular fibers Liver and lymph node assessments $20 to $60 per slide 1-2 business days
Steiner Modified Detects Legionella bacteria Legionella infections in lung tissue; Legionnaires’ disease $20 to $60 per slide 1-2 business days
Warthin Starry Detects spirochetes and bacteria Validating spirochetal infections; Borrelia $20 to $60 per slide 1-2 business days
*The exact cost and timeframes can vary and are subject to change at anytime.

Special Notice for Tissue Submission: Important Shipping Guidelines

Thank you for choosing AniLocus for your histology needs. To ensure the safe and efficient processing of your tissue specimens, please keep the following important guidelines in mind when shipping your samples to our laboratory:

  1. Proper Fixation: Ensure that your tissue specimens are properly fixed in an appropriate fixative solution before shipping. Proper fixation is crucial for preserving tissue integrity and cellular morphology. We recommend a volume:volume ratio of 15:1 to 20:1 for fixative to tissue. Tissue can be submerged in 4% paraformaldehyde/10% normal buffered formalin for no longer than 48 hours in 4ºC or when the tissue sinks in the vial. After 48 hrs, transfer the tissue to 1X PBS at 4ºC for no more than two weeks.
  2. Labeling: Clearly label each specimen container with essential information, including the sample’s unique identifier, the fixative used, the timing of fixation, and any specific handling instructions. Accurate labeling expedites processing.
  3. Secure Packaging: Place fixed tissue containers in leak-proof, sturdy containers or bags to prevent any leakage during transit. Additional padding may be necessary to protect delicate specimens.
  4. Temperature Control: Ship fixed tissue specimens at the appropriate temperature, which may vary depending on the fixative used and specific requirements. Refrigeration or freezing may be necessary for some samples.
  5. Documentation: Include a detailed packing list or submission form with your shipment, listing all the specimens enclosed, their corresponding identifiers, and any specific tests or services requested.
  6. Timely Shipping: Expedite shipping to minimize the time the specimens spend in transit. Ensure that packages are scheduled for delivery during our operational hours.
  7. Shipping Address: Use the correct shipping address provided by our laboratory. Any discrepancies may result in delays or misrouting.
  8. Communication: Inform our team in advance about the shipment by email, including tracking information, to facilitate the tracking and receipt of your specimens.

We appreciate your cooperation and look forward to providing you with high-quality histology services. If you have any questions or require further assistance, please don’t hesitate to contact our customer support team.

Thank you for choosing us as your histology partner.