This test assesses the reinforcement of drug efficacy with the use of a conditioning procedure. Conditioning can be either classical or pavlovian. Animals are tested in either control (non-drug) or experimental (drug) conditions and allowed to explore their environment. Time spent in a preferred environment reinforces the value of the drug being tested. Animals avoid certain environments based on their condition (conditioned place aversion) or spend more time in a drug-associated environment.
- Interior Walls: interchangeable patterned walls (fully customizable)
- Exterior Walls: Grey or Black
- Floors: Interchangeable floors that are easily removed with handles
- Prus AJ, James JR, Rosecrans JA. Conditioned Place Preference. In: Buccafusco JJ, editor. Methods of Behavior Analysis in Neuroscience. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2009. Chapter 4.
- Michael T. Bardo, David B. Horton, Justin R. Yates. Chapter 7 – Conditioned Place Preference as a Preclinical Model for Screening Pharmacotherapies for Drug Abuse. Editor(s): Carrie G. Markgraf, Thomas J. Hudzik, David R. Compton. Nonclinical Assessment of Abuse Potential for New Pharmaceuticals. Academic Press. 2015. Pages 151-196. ISBN: 9780124201729. https://doi.org/10.1016/B978-0-12-420172-9.00007-2.
- Sun, Y., Chen, G., Zhou, K., Zhu, Y. A Conditioned Place Preference Protocol for Measuring Incubation of Craving in Rats. J. Vis. Exp. (141), e58384, doi:10.3791/58384 (2018).