Safety Assessments

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Preclinical CRO Services for Safety Assessment

Hassle-free in vivo safety assessments for pharmaceutical drugs and biologics. Learn More!

Anilocus offers in vivo Safety Assessments for Pharmaceutical Drugs and Biologics. These drug safety studies are crucial for identifying potential safety issues before a drug or biologic is ready for First-in-Human clinical trials.

Our team of scientists implement stringent Good Laboratory Practices (GLP) to conduct rigorous in vivo safety studies for safety pharmacology, pharmacodynamics (PD), pharmacokinetics (PK), and toxicology:

Safety Pharmacology

In vivo Safety Pharmacology studies for drug development are vital experiments performed on living organisms to evaluate the potential risks of drug candidates. These studies aim to examine potential harmful effects on major functional systems such as the cardiovascular, respiratory, and central nervous systems. These studies also test the drug’s effect on renal and gastrointestinal functions. The results of these studies contribute to the assessment of the drug’s safety profile and are used to decide whether the drug should proceed to clinical trials in humans.

Pharmacodynamics (PD)

In vivo pharmacodynamics studies for drug development are studies that enable us to understand the pharmacological effects of a drug. These studies evaluate the biochemical and physiological effects of the drug, the mechanisms of drug action, and the relationship between the drug’s effect and its concentration in the body. This information is crucial for defining the drug’s dosage, efficacy, and safety parameters.

Pharmacokinetics (PK)

In vivo pharmacokinetics studies for drug development are conducted to examine how a drug is absorbed, distributed, metabolized, and excreted (ADME) in a living organism. These studies provide crucial information about the drug’s behavior inside the body, including its bioavailability, half-life, clearance, and volume of distribution. The information obtained can help predict the drug’s safety, efficacy, dosage, and potential interactions with other substances.

Toxicology

In vivo toxicology studies for drug development are experiments conducted to determine the potential toxicity or harmful effects of new drugs or biomaterials used in medical devices. The study measures the drug’s adverse effects at various dosages, how it is absorbed and metabolized, its potential to cause genetic mutations or cancer, and its effects on reproduction. These studies are crucial in ensuring the safety and effectiveness of new drugs before they are approved for clinical trials or released to the market.

 

Our Mission

We support not only pharmaceutical and biotech companies but also medical device companies. Our business model is designed to meet your needs. We provide flexible, scalable solutions that can be tailored to fit your unique requirements.

Whether you are a large pharmaceutical company or a small biotech startup, our services can be customized to help you achieve your drug development goals.

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