Studying Recognition Memory in Animal Models
The ability for animals to discern novel and familiar provides understanding of behavioral responses to novel and familiar objects. Novel objects can alter behavior and provoke stress, repetitive exposure to the novel object can assess these responses and determine when “novel” becomes “familiar”—if at all in the process of the experiment.
In humans, recognition memory is tested with visual comparison where an object and information may be mismatched in order to test proficiency at detecting the errors.
In rodents, recognition memory is assessed using novel object recognition tests and delayed matching/nonmatching to sample tests (DMST OR DNMST). These tests originated in 1970s and have progressed to the novel behavioral tests that exist today.
What is the significance of studying recognition memory?
Recognition memory can be impaired by congenital disorders, neurodegenerative disease, traumatic brain injury, and many other disorders.
Patients with lesions (damage) to the hippocampus have impaired recognition memory formation. Such deficits can be aseessed in primates and rodents to understand the pathophysiology of the damage to the hippocampus and the neural circuitry involved in memory formation.
What We Offer at AniLocus
At AniLocus, we offer multiple novel object recognition mazes and apparatuses that can be used with rodent, fish, or winged insect models to study recognition memory.
Barnes MazeRequest Quote
Bow Tie MazeRequest Quote
Circular Chamber for Novel Object Recognition TestsRequest Quote
Morris Water MazeRequest Quote
Radial Arm MazeRequest Quote
Square Chamber for Novel Object Recognition TestsRequest Quote
Y-Maze TestRequest Quote
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