Dermatology CRO

Dermatology CRO

In Vivo Preclinical CRO Services for Dermatology Drug Development

Looking for in vivo research services for dermatological diseases? Look no further than AniLocus, your collaborator for in vivo preclinical research services for dermatological disease therapies. With millions of lives impacted by skin diseases globally, we understand the urgency of develop innovative treatments.

Our experienced team specializes in comprehensive study implementation, enabling the development of pharmaceutical interventions for various skin diseases. From congenital disorders to rare disorders and environmental exposures, we cover it all. Choose AniLocus, the growing dermatology CRO based in the biotech hub of San Diego. Today, let’s make a difference!

We stand for quality, safety & credibility. Our goal at Anilocus is to support you in the drug development process.

How Can AniLocus Help You?

We are experienced in comprehensive methods for pilot studies and IND-enabling preclinical studies. We are your go-to CRO for in vivo efficacy and safety evaluations! Contact us at anytime!

Contact us! Let’s talk about the science:

    AniLocus In Vivo Services for Dermatology Drug Development

    We utilize ex vivo and in vivo models for skin and connective tissue diseases including:

    • Acne
    • Albinism
    • Alopecia
    • Collagen diseases
    • Connective tissue diseases
    • Dermatitis
    • Eczematous
    • Hair Diseases
    • Neoplasms
    • Psoriasis
    • Rare Genetic Skin Diseases
    • Rheumatic Diseases
    • Skin Cancer
    • Skin Infections
    • Skin Inflammation
    • Skin Microbiome
    • Skin Pigment Disorders (Hypopigmentation/Hyperpigmentation)
    • Ulcerations
    • Vitiligo
    • Wound Healing

    AniLocus In Vivo Services for Dermatology Medical Devices

    We also conduct preclinical toxicology studies to assess medical devices with adhesion for topical and transdermal delivery systems (TDS). We can assist in studies that thoroughly test drug safety, efficiency, efficacy, and consistency.

    Frequently asked questions from Sponsors about in vivo preclinical assessments of dermatological therapies:

    The most common and reliable animal models used to assess the effectiveness of dermatology therapies are rodents, such as mice and rats. These animals are relatively easy to maintain in laboratory settings, and their skin anatomy and physiology closely reflect those of humans.

    Ultimately, they are quite economical, compared to other larger animal models. To assess the efficacy of a given therapy, it is important to use an animal model that closely mimics the clinical setting.

    At Anilocus, animal models can be used to test drug modalities for dermatological diseases. Depending on the type of disease, animal models can be used to test a variety of drugs, such as topical steroids, immune modulators, anti-inflammatory agents, and antifungals.

    When assessing light therapies, animal models can be used to test the efficacy using models such as phototherapy, laser therapy, and ultraviolet light therapy.

    Using animal and human cells and tissue we can perform multiple interrogative assays depending on the therapeutic area, medical device, and/or sample type:

    • DNA: Extraction, PCR, ddPCR, qPCR, sequencing, genotyping
    • RNA: Gene expression profiling, RT-PCR, miRNA, Next-generation sequencing (Nanostring, Illumina), spatial transcriptomics, In situ hybridization (ISH), Multiplex ISH
    • Protein: Immunoassays (ELISA, EIA, Luminex), proteomics, ligand binding assays, protein expression, immunohistochemistry (IHC), immunocytochemistry (ICC), and  immunofluorescence (IF)
    • And more!